Job description:

Join the Vaccine Challenges team within the Tropical Diseases research group, where we're dedicated to tackling diseases caused by Streptococcus pyogenes (Strep A). Our multidisciplinary approach combines both laboratory and clinical research to develop new diagnostic, treatment, and control strategies. We're also focused on deepening our understanding of Strep A's immunology and epidemiology, especially its impact in Australia and developing countries. In collaboration with national and international partners, the team is working towards developing a global Strep A vaccine.

This role includes in-depth microbiological and immunological research and will be under the guidance of the Vaccine Challenges Team Leader, Lab Lead, and Senior Project Coordinator. You'll receive hands-on training and work closely with the Tropical Diseases laboratory team to drive forward innovative lab-based research. Key projects include developing and using a controlled human infection model for Strep A pharyngitis, and using this and other clinical samples to investigate vaccine- and infection-induced immunity (both systemic and mucosal) against Strep A.

Your responsibilities may include:

• Human infection clinical trials: preparation of bacterial challenge doses according to good laboratory practices, processing and storing of human biospecimens
• Immunology: enzyme-linked immunoassays, multiplex antibody and cytokine serology, functional assays and immunophenotyping
• Molecular biology: Nucleic acid extractions and qPCR, transcriptomics of human tissue and bacteria during infection
• Microbiology: Culture of Strep A from human biospecimens
• Tissue culture, aseptic technique, microbiological culture
• Assist and contributes to data generation and results analyses for dissemination in publications, presentations
• Meticulous data entry, continuous maintenance of neat and orderly records, online lab books and data storage
• Ordering and maintaining laboratory supplies

What we need from you:

• Honours or Masters qualification in Biomedical or Biological Sciences or related discipline
• Preferred experience in laboratory-based research, in particular immunology, molecular biology and/or microbiology techniques and a willingness to learn
• Demonstrated capacity to work independently and collaboratively in a team environment and adaptable to suit the needs of the project
• Demonstrated experience in working in an environment where high attention to detail and corresponding recording/reporting is essential
• Excellent time management, organisational and analytical problem-solving skills
• Excellent verbal and written communication skills

For full viewing of responsibilities and requirements please refer to the position description.

Any specific questions related to this position should be directed to Hannah Frost at [email protected].

What's in it for you?

• Maximise Your Pay: Benefit from salary packaging, including entertainment and novated leases
• Flexible Working Options: Enjoy a variety of flexible work arrangements.
• Join a Reputable Organisation: Take advantage of a unique opportunity to be part of a respected research institute
  

Who we are

Murdoch Children's Research Institute envisions a transformative future for child health. Our institute is a hub of impactful scientific breakthroughs, particularly in early interventions, enhanced diagnosis, prevention, and potential cures. We thrive on collaborative, multidisciplinary problem-solving to address challenging queries in child health. Committed to inclusivity and respect, we foster a positive working environment that values diverse backgrounds and experiences. As a proud member of the Australian Network on Disability and a dedicated supporter of Science Australia Gender Equity (SAGE), we uphold principles of equal opportunity and diverse representation.

We are committed to the safety of children and young people and takes a zero-tolerance approach to all forms of child abuse, exploitation and harm. Child safety is prioritised in our decision-making at all levels of the Institute.

Join Us!

If you believe this role is a good fit for you, please apply by submitting:

• Your resume
• A cover letter addressing the selection criteria
  

Ensure these documents are combined into a single PDF file.

We welcome individuals of diverse genders, ages, ethnicities, cultural backgrounds, abilities, religions, and sexual orientations in our workplace. We actively encourage talented individuals from all walks of life to apply for our job openings. Our commitment lies in fostering a workplace that is barrier-free and inclusive, aiming to attract the most skilled candidates.

For any questions related to the recruitment process, feel free to reach out to our Recruitment team at [email protected]. Ensure that you include the position number and job title in the subject line. Please refrain from sharing your application to this email address.

Please note, we reserve the right to close the vacancy prior to the closing date once a sufficient number of applications have been received.

No recruitment agencies please.

Position Description

Applications close: 29 April 2025 AUS Eastern Daylight time

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